X Inactivation and Escape: Epigenetic and Structural Features
نویسندگان
چکیده
منابع مشابه
X-chromosome genetic association test accounting for X-inactivation, skewed X-inactivation, and escape from X-inactivation.
X-chromosome inactivation (XCI) is the process in which one of the two copies of the X-chromosome in females is randomly inactivated to achieve the dosage compensation of X-linked genes between males and females. That is, 50% of the cells have one allele inactive and the other 50% of the cells have the other allele inactive. However, studies have shown that skewed or nonrandom XCI is a biologic...
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ژورنال
عنوان ژورنال: Frontiers in Cell and Developmental Biology
سال: 2019
ISSN: 2296-634X
DOI: 10.3389/fcell.2019.00219